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耐药性结核离我们远吗
2017-08-15 09:44:49 中国青年网
耐多药结核病:是指结核病患者感染的结核分枝杆菌体外DST证实至少同时对异烟肼和利福平耐药的结核病。
广泛耐药结核病:是指结核病患者感染的结核分枝杆菌体外DST证实除至少同时对异烟肼和利福平耐药外,还对任何氟喹诺酮类抗菌药物产生耐药,以及3种二线注射类药物(卷曲霉素、卡那霉素和阿米卡星)中的至少1种耐药的结核病。
利福平耐药结核病:是指结核病患者感染的结核分枝杆菌体外DST证实对利福平耐药的结核病,包括任何耐利福平的结核病,即利福平单耐药结核病、利福平多耐药结核病、耐多药结核病和广泛耐药结核病等。
■ 我省九成结核发生在学校
肺结核目前仍是我省第一大传染病,江苏平均每天大约有100多人患上肺结核,超过九成的结核病聚集性疫情发生在学校。
近年来,我省报告的甲、乙类法定报告传染病发病中肺结核每月的发病数都在3000人左右,肺结核报告发病数和死亡数仍然位居江苏甲、乙类法定传染病报告的前列,占到了江苏省法定传染病人数总和的四成左右。
张侠说,耐药型肺结核目前受缺乏有效的抗结核新药物、结核患者的经济水平低、地域差异、药物不良反应多、依从性差、耐药肺结核诊断延误等多种原因的制约,使得治愈率低、缺乏统一标准的治疗方案。这就需要我们及早发现结核病传染源,并控制住传染源、切断传播途径,同时建立健全的结核病监测体系、预测评估技术指标、研发新的检测方法、开发结核病新药物、制定合理抗结核方案。
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