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成人肥胖或是线粒体故障所致

2017-08-20 11:21:26   中国青年网

新华社堪培拉8月20日电(记者徐海静)澳大利亚科学家最新发现,成人肥胖可能是细胞内线粒体的基因表达出现了问题。

线粒体是细胞中提供能量的细胞器,被称作细胞的“能量工厂”,有着自己的遗传物质。

西澳大利亚大学等机构研究人员日前在美国《科学进展》杂志上报告说,他们通过小鼠实验发现,如果线粒体中PTCD1基因表达受损,线粒体形态就会发生变化,无法正常将脂肪和碳水化合物转化成能量,进而引发成年人肥胖,患脂肪肝、心脏肥大等疾病。

研究人员说,实验表明,线粒体基因表达出现问题对能量代谢有着长期影响,了解其中机制可更有针对性地开发治疗肥胖、脂肪肝等疾病的药物和方法。

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