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媒体6问生物细胞免疫疗法:在美国已宣告失败

2016-05-03 03:35:37   新京报

记者通过百度搜索进入“上海新科医院肝病科官方网站”,该页面上详细介绍了“免疫细胞疗法”的具体治疗步骤。该医院网页介 绍,在治疗过程中,第一天对患者进行细胞提取,第七天对其进行临床注射,在回输7天后,患者开始第二次的细胞治疗过程,每月只需治疗2次,3-6个月为一 个疗程。

昨天,记者通过百度搜索进入“济南中山医院”网页界面,以乙肝大三阳患者身份咨询其页面弹出的一位“王医生”,王医生一开始不愿透露DC细胞生物免疫疗法的具体情况,在记者再三追问下,王医生表示,治疗一疗程价格在一两千元左右。

“吉林中山医院”的相关网页则介绍,此疗法治疗乙肝大三阳一个疗程的费用在千元以内,具体费用根据不同情况,从几百到几千元不等。

记者在百度知道中搜索发现,2015年12月25日,一位名为“温洪泽肿瘤医生”的用户回复网友询问表示,细胞生物免疫疗法治疗癌症的费用,一个疗程在 3万元左右,不同地区、不同医院治疗费用可能有所不同。这位温洪泽医生的基本资料中自称是武警北京总队第二医院肿瘤生物中心主任医师,居住地为北京市西城区。

  疑问3“免疫治疗技术”是否成熟?

魏则西在武警北京总队第二医院使用的是“DC免疫治疗技术”,近日引发争议。郝纯毅解释,实际上DC免疫治疗技术本身是很成熟的技术,关键是如何应用。

据郝纯毅介绍,“免疫治疗”的原理是调动患者自身抵抗力、战斗力抵御肿瘤细胞,而非像化疗、放疗等的“直接杀伤”。在理论上来讲,这是肿瘤治疗的一个发展方向,也是当前肿瘤治疗学领域中的研究热点之一。

不过,郝纯毅指出,免疫治疗对于某些病种的治疗效果比较好,像肾癌、黑色素瘤、淋巴瘤等,在很多医院均有开展。但对于很多肿瘤而言,免疫治疗目前还处于研究阶段,并没有取得明显效果。对于魏则西所患的滑膜肉瘤,使用免疫治疗并不是成熟的治疗方法。

国内一些研究者提供的数据显示,使用DC-CIK疗法后,一些病人的远期生存率有所提升。在一项天津肿瘤医院发起的研究中,DC-CIK治疗使非小细胞肺癌患者的一年生存率提高近20个百分点。但直到目前,尚未有直接证据证明,这一疗法能在根治癌症上起到决定性作用。

据微信公众号“知识分子”报道,CIK或DC-CIK疗法此前已在美国经历多年研究,但其相关临床试验在美国基本全部宣告失败,绝大多数基于该方法的治疗技术均未得到上市批准。目前,美国已鲜有DC-CIK疗法的临床试验。

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