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睡不着睡不香睡不好?研究称睡眠不好或怪肌肉

2017-08-12 07:02:15   新华网

美国得克萨斯大学的一项研究显示,肌肉中一种蛋白质可能影响睡眠,能够帮助调节睡眠时长和质量。按照先前研究结果,大脑发出化学信号引人入睡,这就令人以为,睡眠紊乱得怪大脑,而得克萨斯大学这项研究显示,肌肉也起作用。

研究涉及的蛋白质名为BMAL1。这种蛋白质能够调节昼夜节律,动物实验显示,去除这种蛋白质会影响一系列睡眠行为,但尚不清楚其中作用机制。得克萨斯大学研究小组详细研究了小鼠大脑和肌肉中存在或缺乏BMAL1时,睡眠质量、睡眠时长、缺觉后恢复能力等睡眠行为会受怎样的影响。

结果显示,当小鼠大脑中的BMAL1蛋白被清除后,睡眠行为未受影响;把BMAL1重新注入大脑,睡眠行为也未发生改变。但当肌肉中的BMAL1被清除后,小鼠不仅出现严重的睡眠中断现象,而且需要更长的睡眠时间,缺觉后恢复能力也变弱;当研究人员把BMAL1蛋白重新注入小鼠肌肉后,缺觉后恢复能力又回到正常。

研究结果刊载于美国《电子生命》期刊。今日医学新闻网站援引研究人员的话报道,这项结果“完全出人意料”,显示睡眠进程不单受大脑控制。研究人员说,肌肉能向大脑发送信号,进而影响睡眠,“如果人类身上存在类似通路,可能给睡眠紊乱治疗提供新方法”。(黄敏)【新华社微特稿】

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