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世界最新抗癌药中国也能造 一年治疗费用不超10万

2017-04-28 00:30:27   央视财经

在苏州吴江区的生产线上。由美国实验室研发出来的抗体就在这里进行工艺开发及生产。目前武海的研发团队已经有两个项目被立为国家新药创制重大专项。其中抗癌药PD-1单抗正在中国医科院肿瘤医院进行一期临床试验。

中国医学科学院肿瘤医院副院长石远凯:进口的药物即使在中国上市了,它的价格肯定不是一般老百姓能用得起的,如果国产的药物上市了,它的价格肯定要比进口的药物要便宜很多,所以能够惠及到我们中国的广大普通的患者。

一只小白鼠要五万美金!新药研发考验中国实力

单抗药物治疗因其靶向、低毒、疗效好,被广泛应用在肿瘤、自身免疫病、病毒感染、骨质疏松、心脑血管等领域。但是单抗药物开发存在着成本高、难度大、产能有限等特点,对研发公司的技术、资金都有着极高的要求。我国单抗药物的研发和国际先进水平相比还有不小的差距。

国际上通常用“生物反应罐”的规模作为其中一个标准,来衡量一个国家生物制药的产业水平。美国总规模约为130万升,韩国约为57万升,而中国只有5万升,不到美国的4%。

上海君实生物医药科技股份有限公司副总经理张卓兵:制造环节刚才说了设备都是人家的,我们在技术环节里,像培养基,像一些分析方法,分析的试剂都是国外的。

为了能够在药物研发领域与国际接轨,这群中国的科研人员,先后在美国旧金山和马里兰设立了两个实验室,负责药物前端的研发工作。

在上海君实位于美国马里兰的肿瘤免疫实验室,君实的创始人之一姚盛在负责肿瘤药物的靶点开发。姚盛告诉央视财经《经济半小时》记者,绝大多数的人体内时时刻刻都有肿瘤细胞和免疫细胞在发生战斗,这里的工作就是通过观察细胞之间、蛋白质之间的作用,来发现帮助免疫细胞战胜癌细胞的方法。

目前已知的人体细胞膜受体蛋白有大约6000种,而不同的肿瘤与这些受体之间的关系可以说是千变万化,随机寻找有用的靶向无异大海捞针,君实公司目前也在积极搜集许多战胜了癌症的病人的生物样本,寻找新的战胜癌症的抗体。

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