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肺癌患者国内求医被“判死刑” 赴美治愈可跑步

2016-08-20 04:02:08   中国新闻周刊

虽然肺癌在中国的5年存活率为16.1%,与美国的17%十分接近,但就癌症治疗的总体水平而言,中国癌症发病率接近世界水平,而死亡率却高于世界水平。数据显示,美国癌症患者5年存活率在60%至70%,而中国癌症患者的5年存活率仅在30%左右。

活检和基因检测为李明磊找到了患癌的精确病因——EGFR19基因突变。他说:“在国内,这种情况几乎没治。但在美国,当时已经有了针对EGFR19基因突变的第二代特效药阿法替尼,第三代药物AZD9291的临床试验也已经进行到了第Ⅲ期。”于是,他决定去美国去“碰碰运气”。

在经过一系列非常专业的病历资料准备以后,李明磊选定在全美综合医院名列前茅的麻省总医院就诊。按照预约时间赴美以后,到达波士顿的第二天他就前往医院去见医生。美国医生一边叫他“李医生”,一边起身与他握手。肿瘤科专家还为他约了一位胸外科医生,共同讨论治疗方案。

与国内医生的意见不同,美国医生告诉李明磊,在靶向药物治疗见效后,剩下的原发病灶可以再行手术治疗。

盛诺一家创始人兼董事长蔡强告诉《中国新闻周刊》(微信ID:china-newsweek),在去美国就医后,有67%的中国患者的治疗方案被改变。原因之一是,美国的临床医学正在向“精准医疗”的方向发展,一个患者往往由多个学科的医生共同诊治,在这种理念下他们相信,“没有任何两个肺癌病人的治疗方案是相同的”。

治疗方案被改变的另一个原因则在于药品的差异。“大量的癌症患者到美国选择了新的治疗方案,因为我们最新的药品是美国2011年上市的,美国2012年、2013年…… 一直到2016年的药,我们都没有。”

蔡强举例说,他们介绍过一个皮肤癌患者去美国看病,结果,美国的医生发现,中国用的药是美国30年前的。

实际上,中国医生基于国内上市的药品而给患者制定的治疗方案并没有错误,只是药物不够先进。在新药研发落后的情况下,中国医生难为无米之炊。一位患者在美国取得了满意的治疗效果后这样说:“这就好像美国都在用iPhone6了,我们还在用iPhone3。当然,这只是一个不够恰当的比喻,在手机方面,中国人是完全不甘落伍的。”

皮肤黑色素瘤患者张天银在北京一家三甲医院治疗,他的主治医生李陶建议,可以考虑去美国参加临床试验。刚刚参加完全美肿瘤学年会的李陶告诉《中国新闻周刊》(微信ID:china-newsweek):“当时我们知道,美国已经有了专门针对黑色素瘤的新药,正在做Ⅲ期临床试验,而且Ⅰ期、Ⅱ期试验的结果显示,疗效非常好。但是,中国还没有这方面的药物和临床试验,对于有条件出国就医的患者,我会建议他们去国外选择最新的药物治疗。”

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