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英国研究:降糖药或可阻止帕金森病进展

2017-08-25 20:00:58   中国青年网

人民网伦敦8月25日电 发表于《柳叶刀》的一项对62名病人的试验表明,一个通常用于治疗2型糖尿病的药物艾塞那肽有可能阻止帕金森病的进展。

据英国广播公司报道,伦敦大学学院(UCL)的团队对研究结果表示“兴奋”,但也谨慎地表示,长期效果尚不确定,需要更多的药物测试。

目前治疗帕金森病的药物主要是缓解症状,却不能阻止脑细胞死亡。研究团队表示,毫无疑问,目前治疗帕金森病最重要的是需要一种药物延缓疾病的进展。

帕金森病患者的大脑受到了破坏,产生多巴胺的细胞丢失,从而导致震颤、移动困难、最终导致记忆问题。目前的治疗有助于通过增加多巴胺水平来缓解症状,但大脑的死亡仍在继续,尚无药物来阻止病情恶化。

研究团队表示,虽然实验确实表明艾塞那肽带来的改善,但是帕金森病的进展缓慢,这60周试验对日常生活的影响是“微不足道的”还需要对药物进行更长时间的试验。

英国帕金森病专家David Dexter表示:因为帕金森的进展相当缓慢,这项研究规模可能太小且时间过短,但是是令人鼓舞的,值得进一步研究。(璗译)

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