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央视:韩春雨正实验研究论文结果无法重复原因

2017-05-21 01:26:13   

原标题:新闻调查:副教授韩春雨

韩春雨 资料图

学界和媒体的热议

一年前,英国《自然 生物技术》杂志刊载了一篇有关“基因编辑工具”的论文。论文的负责人“一鸣惊人”,得到了学界和媒体给予的无限荣光。

在《自然》杂志社的所属期刊上发表论文,通常表明,该科研成果走在了世界科学研究的最前沿,并有可能对未来科学的发展起到关键性作用。

发表论文通讯作者韩春雨,来自河北科技大学,在生物技术领域几乎名不见经传。但是,这并不妨碍这篇论文在华人生物界获得广泛赞誉。众多科学界人士认为,“我们的体制应当更多地支持那些对研究有兴趣有耐得住寂寞的学者”。

在学界得到热烈讨论的基因组编辑技术是当下基础科学研究的重点项目之一。作为我国基因编辑领域最前沿的科学家之一,北京大学生命科学院教授魏文胜称,“这是一个所谓革命性的技术。能够治疗以前想治不能治的病,比如说像遗传病,可以通过修改基因组序列进行治疗,从某种意义上面讲,有点像扮演上帝的角色”。同时他也表示,“正是因为国内的这种底层原创技术太少,才会产生这种格外激烈地反应”。

目前生物学界,可以成功实现人为介入基因组所必不可少的“剪刀”是由美国华裔科学家张锋、美国科学家詹妮弗·杜德纳及法国科学家埃马纽埃尔·卡彭蒂耶为主要技术开发者的CRISPR-Cas9技术。而韩春雨论文中所述的NgAgo技术,被视为挑战前者的一把“新剪刀”,也可实现对目标基因的有效切割。

这项研究成果,也很可能打破国际基因编辑技术的垄断,具有极高的科研和商业价值。上海华东师范大学生命医学院教授李大力认为,“如果NgAgo技术能够拿到专利的话。就可以回避CRISPR的技术的限制,很多的问题就可以利用NgAgo来解决了”。

论文发表后,生物学相关专业的实验室也竞相去重复他的实验,希望迅速掌握这把新“剪刀”。很快,北京大学魏文胜实验室就宣称了实验重复成功。

名不见经传的韩春雨,在一夜之间成为了业内炙手可热的科学家。曾经发现他才华的前河北科技大学生物工程学院院长也感叹韩春雨所取得的成果,并给予了祝贺。在回忆初次见到韩春雨时,他也表示,“初次见到韩春雨时,就感觉他很聪明,就新生喜欢”。

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