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郑州大学教授芹菜中提取脑梗药 专利卖4500万(图)

2014-11-26 15:05:31   中新网

郑大教授常俊标(右二)

核心提示|50多个人,研究13年,最终从芹菜中提取了一个活性成分,然后利用此成分对现有的药进行改造,制作成了一种新的治疗脑梗药

昨天,在郑州大学,这个新药被以4500万元的价格转给药企。明年四五月份,该药将进入临床试验,如果一切顺利,预计4年后,此药将可走进患者生活中。

作为此组科研的领头人,郑州大学副校长常俊标的下一个目标是,带领团队,攻克丙肝和肝癌。

芹菜中挖的“宝”4500万元转让专利转让|

11月25日上午,在郑州大学新校区第五会议室内,郑州大学和浙江奥翔药业有限公司签下协议,常俊标将自己研发的“一类新药布罗佐喷钠”以4500万元的价格转让给该公司。

很多时候不是有了希望才坚持,而是因为坚持才有了希望。

“我确实幸运,有些人一辈子也研究不出来一种药,机遇真的很重要。”药品研发的艰辛不必赘言,但在常俊标眼里制药有着他人无法想象的乐趣。

“后面有个东西追着似的,非得让你快点走不可。这个过程当然辛苦,可辛苦之余也有乐趣。就是解决完一个困难,大伙还没高兴完呢,第二个困难又来了,再想办法解决。我就觉得又紧张又挺高兴的。”可以想见,过程绝非常俊标轻描淡写般简单,仅在治疗脑梗药物中寻找制剂一项,就用了8年时间。实验中换了多少种化合物,他自己都记不清了。

看不到希望!放弃吧!当团队的其他成员一个个打退堂鼓时,常俊标却拍板决定--继续做!

正是这样的坚持,让他们最终从芹菜中提取了活性成分进行结构优化。

怎么想到从芹菜中挖宝呢?“芹菜本身就对降血压,对脑血管有好处。”常俊标说,最终,他带领50多人,研究13年,利用从芹菜中提取的活性成分,进行结构优化,制作成了这种新“脑梗药”--布罗佐喷钠。50人的队伍中,年龄最大的91岁。

在他规划的蓝图中,新药明年四五月份进入临床,如果一切顺利,4年后,此药可以投产,走进患者生活。

投产后200万脑梗患者将受益患者福音|

得此消息后,常年在临床工作的郑大一附院神经内科主任许予明教授表示很期待。

许予明介绍,脑血管疾病是导致人类死亡的三大疾病之一,在全球范围内,每年约460万人因此死亡,其中1/3在工业化国家,其余发生在发展中国家,我国是脑卒中死亡率高发地区,而我省更是重灾区。

“中国每年新发脑血管病200万人,我省占到十分之一还要多。”许予明说,目前,对于脑梗病人,除了血管再通治疗尚有效外,其他疗法效果都很微弱,临床急需寻找这样一种药。

在许予明看来,目前,用于治疗脑梗的脑保护药有许多种,但是这些药大多效果不确切或者效果微弱,只有丁基苯酞有一定疗效,但是也有一定的副作用。

“新药布罗佐喷钠,相当于丁基苯酞的升级版,目前动物临床试验效果很好,副作用也很小,将来有望成为真正的脑保护药。”许予明期盼,该药顺利通过临床试验,然后尽快投产,造福脑梗患者。

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