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国产抗癌新药入选医保目录 救命药每月仅花1千元

2017-09-01 01:19:42   央视财经

和张宗英一样,深圳市的吴敏也是被从死亡线上抢救了回来的一名患者。2013年,吴敏被确诊为T细胞淋巴瘤晚期,当时国内没有分子靶向药物,只能通过常规化疗进行治疗,吴敏对长期化疗的耐受性很差,2014年甚至出现了长达两个月的深度昏迷。

癌症的折磨和化疗产生的不良反应,让吴敏难以承受,生命垂危,深圳北大医院给家属一连下了几张病危通知书。

吴敏的丈夫王成:内心已经要崩溃了。想着几十年相濡以沫的老伴就要走了,你说能不难受吗,小孩过来也是哭的不行。

在医生的抢救下,吴敏虽然一次次闯过了鬼门关。但是每次苏醒过后,又面临着下一次的昏迷。2015年,在吴敏经过两年的折磨之后,一种抗癌创新药——西达本胺问世,吴敏和家人抱着试试看的想法,开始尝试使用这个新药,令人惊喜的是,病情居然被控制住了。现在吴敏一直坚持服药,病情稳定,生活质量也非常好。

吴敏:比原来好一些,也没有再出现水肿、发烧、起红疹这些,都没有再出现了。

【国产药引发轰动国外药企首次从中国引进专利进行开发】

T细胞淋巴瘤,是恶性程度非常高的肿瘤,这种病在我国的初发和复发患者每年约为5万人,五年存活率仅为25%。我们刚刚看到的两名患者,在服用西达本胺之后,病情得到了有效的控制。那么西达本胺是一种什么样的抗癌新药呢?

西达本胺是我国自主研发的抗癌新药,研发单位是深圳一家名为微芯生物公司的企业,在数十万次的实验中,这支专注创新的研发团队发现了高分子物质酶,这种酶几乎活跃在所有的细胞活动中。西达本胺通过精确控制与肿瘤细胞活动密切相关的四种酶,激活人体内抗肿瘤细胞的免疫功能,来控制肿瘤复发和转移。

深圳微芯生物科技有限责任公司总裁兼首席科学官鲁先平:西达本胺是一种组蛋白去乙酰化酶抑制剂,它在调控基因表达中起着一个非常关键的作用机制,也就是说把好的基因给关掉了,把坏的基因给打开了,所以我们通过西达本胺这个抑制剂,我们重新把这个过程逆转,让好的基因重新打开,坏的基因被关掉,我们把不受控制的细胞,通过重新编程又让它回归到可控制的状态,通过这么一个作用机制,把肿瘤停止生长变为可能,肿瘤就得到有效的控制。

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