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孕期服用抗抑郁药可能略增孩子自闭症风险

2017-07-22 13:17:25   新华网

新华社伦敦7月21日电(记者张家伟)一个国际团队在《英国医学杂志》发表报告说,基于大量人群健康数据的分析发现,如果女性在怀孕期间服用抗抑郁药,可能会略微增加她们所生孩子患自闭症的风险。

英国布里斯托尔大学等机构的研究人员尝试利用多种分析方法来梳理2001年至2011年间采集自瑞典的人群健康数据,这其中涉及超过25万名居住在斯德哥尔摩的少年儿童,年龄从4岁到17岁不等,其中5378人患有自闭症。

结果显示,3342人的母亲在怀孕期间曾服用抗抑郁药,这些人中有4.1%被诊断出患自闭症。相比而言,超过1.2万人的母亲尽管有精神病史但并未在怀孕期间服用抗抑郁药,这些人中仅有2.9%患自闭症。

研究人员指出,用不同分析方法得出的结果基本相符,不过总体上的绝对风险仍然很小——超过95%怀孕期间曾服用抗抑郁药的妇女,她们生出来的孩子都没有患自闭症。

研究人员表示,尽管这项研究的人群样本比较多,也采用了多种分析方法,但研究本身还有不少局限性,比如缺乏抑郁程度等详细信息,因此还无法得出确切结论,需要进一步的研究来确认。

报告作者、布里斯托尔大学的迪拉杰·拉伊说,如何平衡怀孕期间服用药物的益处和风险,这是个复杂和困难的抉择,“我们的建议是女性应该与她们的主治医生讨论自己的担忧,医生能帮她们衡量其中的利弊”。

责任编辑:韩佟 CL1368
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